Antiviral Remdesivir Prevents Disease Progression in Monkeys with COVID-19
by National Institutes of Health
Early treatment with the experimental antiviral drug remdesivir significantly reduced clinical disease and damage to the lungs of rhesus macaques infected with SARS-CoV-2, the coronavirus that causes COVID-19, according to National Institutes of Health scientists.
The study was designed to follow dosing and treatment procedures used for hospitalized COVID-19 patients being administered remdesivir in a large, multi-center, clinical trial led by NIH’s National Institute of Allergy and Infectious Diseases (NIAID). The scientists posted the work on the preprint server bioRxiv. The findings are not yet peer-reviewed and should not be considered clinical advice, but are being shared to assist the public health response to COVID-19. A study detailing the development of the rhesus macaque model of mild- to-moderate human disease, conducted by the same team of NIAID scientists, was posted to bioRxiv on March 21.
The current study of remdesivir, a drug developed by Gilead Sciences Inc. and NIAID-supported investigators, involved two groups of six rhesus macaques. One group of monkeys received remdesivir and the other animals served as an untreated comparison group. Scientists infected both groups with SARS-CoV-2. Twelve hours later the treatment group received a dose of remdesivir intravenously, and then received a daily intravenous booster dose…read more:
Carol graduated from Riverside White Cross School of Nursing in Columbus, Ohio and received her diploma as a registered nurse. She attended Bowling Green State University where she received a Bachelor of Arts Degree in History and Literature. She attended the University of Toledo, College of Nursing, and received a Master’s of Nursing Science Degree as an Educator.
She has traveled extensively, is a photographer, and writes on medical issues. Carol has three children RJ, Katherine, and Stephen – one daughter-in-law; Katie – two granddaughters; Isabella Marianna and Zoe Olivia – and one grandson, Alexander Paul. She also shares her life with her husband Gordon Duff, many cats, and two rescues.
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Are ventilators doing more harm than good?
Some intensive care units have started to delay putting a Covid-19 patient on a ventilator to the last possible moment
https://asiatimes.com/2020/04/are-ventilators-doing-more-harm-than-good/
A COVID-19 treatment rethink? Apparently, some front line doctors are now saying that ventilators may cause more harm than good; that you can’t treat the infection like pneumonia, that acutely, the symptoms more represent altitude sickness, citing appalling mortality statistics among those groups of patients placed on ventilators.
https://www.dailymail.co.uk/news/article-8230775/Is-proof-live-saving-ventilators-actually-deathtraps.html
Be wary of the Mail as a source, they are often full of it. One thing that is being tried here in Britain is the use of CPAP machines on patients that aren’t quite ill enough to need to be put on a ventialtor, CPAP uses air pressure to force air into the lungs and doesn’t require inducing a coma like being put on a ventilator does.
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