NEJM: Hydroxychlorquine no better than placibo-study

Trial suggests drug does not protect those exposed to virus from becoming infected

Republican presidential candidate Donald Trump responds to former Arkansas Gov. Mike Huckabee's closing remarks during the first Republican presidential debate at the Quicken Loans Arena Thursday, Aug. 6, 2015, in Cleveland. (AP Photo/Andrew Harnik)


Guardian: Taking hydroxychloroquine does not protect people who have been close to someone with coronavirus from becoming infected, a study suggests.

Donald Trump told the world he was taking one pill a day to safeguard himself against the coronavirus, on the advice of his doctor. However, a study published in the New England Journal of Medicine suggests the drug is no more effective in protecting people exposed to the virus than a placebo.

The trial, which was carried out in the USand Canada, recruited people who were at moderate to high risk of contracting Covid-19. Most of them were deemed at high risk because they had been closer than 2 metres from somebody with the virus for more than 10 minutes without wearing any personal protective equipment. The hope was that the drug could be used to protect people where somebody in their family was infected.

This was a randomised, controlled trial – the so-called “gold standard” – and was set up to compare what happened in people given hydroxychloroquine within four days of exposure and those given dummy pills instead.

The researchers enrolled 821 mostly younger and healthy adults with an average age of 40 who had no symptoms at the time. Within four days of exposure, each received a delivery from a courier of a package containing either placebo or hydroxychloroquine. The pills were to be taken over five days, starting with a stronger dose on day one.  read more…



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  1. A hole in the Bucket ? WHO announced WED. it is set to resume Hydroxychloroquine studies in treating Covid 19 virus . But , hey , more ‘ facts ‘ from a reliable institution will be announced for your discerning pleasure .
    WHO do you Trust ?
    I took anti malarial drugs for 13 months in Viet Nam , still here 52 years later , Agent Orange exposure symptoms are more dangerous outlook , barely recognized lately by .gov . and culling Vets in mass.

  2. Again, another article mentioning a hydroxychloroquine study WITHOUT combining it with anything else. Alas, it has been shown to be effective ONLY when combined with Zinc as hydroxychloroquine cannot kill the virus by itself (from the studies I’ve come across and they mention this fact). The motives of articles such as this surprise me. Either they’re not aware of the hydroxychloroquine/Zinc studies or are intentionally trying to publish the image of “Hydroxychloroquine ineffective against Covid-19”. Ask yourself this: Why is it an occasional surfer like myself can come across studies that show this combination to work and not ones who write articles on the subject?

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