NIH: Defeating COVID-19 Requires Unprecedented Action and Collaboration

Colorized scanning electron micrograph of a VERO E6 cell (purple) exhibiting elongated cell projections and signs of apoptosis, after infection with SARS-COV-2 virus particles (pink), which were isolated from a patient sample. Image captured at the NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland. NIAID

Director: Defeating COVID-19 requires unprecedented action and collaboration

NIH:Media Advisory News Release

To respond to the generational public health crisis caused by the global COVID-19 pandemic, a swift, coordinated effort across many sectors of society is necessary, say National Institutes of Health (NIH) Director Francis S. Collins, M.D., Ph.D., and Johnson & Johnson Vice Chairman of the Executive Committee and Chief Scientific Officer Paul Stoffels, M.D. In a Viewpoint published today in JAMA(link is external), Drs. Collins and Stoffels outline the innovative efforts of Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV), a public-private initiative organized by NIH and the Foundation for the NIH. ACTIV’s partners, which include at least 18 leading biopharmaceutical companies, multiple U.S. federal agencies, and the European Medicines Agency, are developing an international strategy for an integrated research response to COVID-19.

Noting that never has a public-private biomedical research effort of this scope and scale come together with such speed and determination, Drs. Collins and Stoffels describe how ACTIV has established a collaborative framework to prioritize therapeutic and vaccine candidates; to streamline human clinical trials and tap into existing trial networks; and to coordinate regulatory processes and leverage assets among all partners.

Read More:


Collins FS, Stoffels P. Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV): An Unprecedented Partnership for Unprecedented Times(link is external). JAMA. DOI: 10.1001/jama.2020.8920 (2020).


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  1. Absolutely right, Mrs. Duff. All those diseases killed homo sapiens from childhood, when immune system was bare. We had brilliant Soviet virologists and vaccines helped us to forget about these diseases. And to help poor countries, too.
    All Soviet citizens have a round scar on their left shoulder. This is a vaccination against smallpox and tuberculosis. It was made on the 4th day after birth. By this scar, you can always recognize a person from the USSR. And we had a strong and healthy nation.

  2. Rpm1945, In general people can have a robust immune system, but many bacteria and viruses can move into these individuals and make them sick and/or dead. Viruses use body cells to replicate…Viruses do not have the ability to make more of themselves unless they hijack a body cell. They then use the replication process, inherent in body cells, to make more virus. We have never had immunity to polio, tetanus, diphtheria, measles, mumps, rubella, meningitis, types of hepatitis norovirus, influenza. If we had not had vaccines developed for these diseases, we would be a population of far less numbers. Healthy immune systems can do just so much, but even they are not immune to bacterias and viruses that like to use humans to replicate. A virus has developed the perfect ability to multiply and spread by using humans as the host.

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